Sulfafurazole

Not to be confused with sulfadiazine.

Sulfafurazole
Clinical data

AHFS/Drugs.com	International Drug Names
MedlinePlus	a601049
Pregnancy category	To be avoided within two months of term
Routes of administration	Oral
ATC code	J01EB05 (WHO) S01AB02 (WHO) QJ01EQ05 (WHO)
Legal status
Legal status	℞ (Prescription only)
Pharmacokinetic data
Excretion	Excreted unchanged in urine
Identifiers
IUPAC name 4-Amino-N-(3,4-dimethyl-1,2-oxazol-5-yl)benzenesulfonamide
CAS Number	127-69-5^Y
PubChem (CID)	5344
DrugBank	DB00263^N
UNII	740T4C525W^N
KEGG	D00450^Y
ChEMBL	CHEMBL453^N
ECHA InfoCard	100.004.418
Chemical and physical data
Formula	C₁₁H₁₃N₃O₃S
Molar mass	267.30 g/mol
3D model (Jmol)	Interactive image
Melting point	194 °C (381 °F)
SMILES CC1=C(ON=C1C)NS(=O)(=O)C2=CC=C(C=C2)N
^NY (what is this?) (verify)

Sulfafurazole (INN, also known as sulfisoxazole) is a sulfonamide antibacterial with an oxazole substituent. It has antibiotic activity against a wide range of Gram-negative and Gram-positive organisms. It is sometimes given in combination with erythromycin (see erythromycin/Sulfafurazole) or phenazopyridine. It is used locally in a 4% solution or ointment.

External links

Antifolates
(inhibits
purine metabolism,
thereby inhibiting
DNA and RNA synthesis)

Short- acting	Sulfaisodimidine Sulfamethizole Sulfadimidine Sulfapyridine Sulfafurazole Sulfanilamide Prontosil Sulfathiazole Sulfathiourea

Intermediate- acting	Sulfamethoxazole Sulfadiazine^# Sulfamoxole

Long- acting	Sulfadimethoxine Sulfadoxine Sulfalene Sulfametomidine Sulfametoxydiazine Sulfamethoxypyridazine Sulfaperin Sulfamerazine Sulfaphenazole Sulfamazone

Other/ungrouped	Sulfacetamide Sulfadicramide Sulfametrole

Combinations

2nd g.	Ciprofloxacin^# Ofloxacin Enoxacin^‡ Fleroxacin^‡ Lomefloxacin^‡ Nadifloxacin^‡ Norfloxacin^‡ Pefloxacin^‡ Rufloxacin^‡

3rd g.	Levofloxacin Balofloxacin^‡ Grepafloxacin^‡ Pazufloxacin^‡ Sparfloxacin^‡ Temafloxacin^‡ Tosufloxacin^‡

4th g.	Besifloxacin Gatifloxacin Finafloxacin Gemifloxacin Moxifloxacin Clinafloxacin^† Garenoxacin^‡ Prulifloxacin^‡ Sitafloxacin^‡ Trovafloxacin^‡/Alatrofloxacin^‡

Vet.	Danofloxacin Difloxacin Enrofloxacin Ibafloxacin Marbofloxacin Orbifloxacin Pradofloxacin Sarafloxacin

Newer non-fluorinated

Related (DG)

Nitro- imidazole derivatives	Metronidazole^# Tinidazole Ornidazole

Nitrofuran derivatives	Nitrofurantoin^# Furazolidone^‡ Nifurtoinol

RNA synthesis

Rifamycins/ RNA polymerase	Rifampicin^# Rifabutin Rifapentine Rifaximin Rifalazil^§

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