| Office | Name | Date | Notes |
Prime Minister and Leader of the House of Lords | The Marquess of Salisbury | 25 July 1886 – 11 August 1892 | |
| First Lord of the Treasury | The Marquess of Salisbury | 9 August 1886 | |
| William Henry Smith | 17 January 1887 | also Leader of the House of Commons |
| Arthur Balfour | October 1891 | also Leader of the House of Commons |
| Chancellor of the Exchequer | Lord Randolph Churchill | 3 August 1886 | also Leader of the House of Commons |
| George Goschen | 14 January 1887 | |
| Parliamentary Secretary to the Treasury | Aretas Akers-Douglas | 3 August 1886 | |
| Financial Secretary to the Treasury | William Jackson | 3 August 1886 | |
| Sir John Eldon Gorst | 9 November 1891 |
| Junior Lords of the Treasury | Sidney Herbert | 9 August 1886 – 11 August 1892 | William Walrond inherited a baronetcy in 1889 |
| William Walrond | 9 August 1886 – 11 August 1892 |
| Sir Herbert Maxwell, Bt | 9 August 1886 – 11 August 1892 |
| Lord Chancellor | The Lord Halsbury | 3 August 1886 | |
| Lord President of the Council | The Viscount Cranbrook | 3 August 1886 | |
| Lord Privy Seal | The Earl Cadogan | 3 August 1886 | entered the Cabinet April 1887 |
| Secretary of State for the Home Department | Henry Matthews | 3 August 1886 | |
| Under-Secretary of State for the Home Department | Charles Stuart-Wortley | 4 August 1886 | |
| Secretary of State for Foreign Affairs | The Earl of Iddesleigh | 3 August 1886 | |
| The Marquess of Salisbury | 14 January 1887 |
| Under-Secretary of State for Foreign Affairs | Sir James Fergusson, Bt | 4 August 1886 | |
| James Lowther | 22 September 1891 |
| Secretary of State for War | William Henry Smith | 3 August 1886 | |
| Edward Stanhope | 14 January 1887 |
| Under-Secretary of State for War | The Lord Harris | 4 August 1886 | |
| The Earl Brownlow | 1 January 1890 |
| Financial Secretary to the War Office | St John Brodrick | 4 August 1886 | |
| Surveyor-General of the Ordnance | Sir Henry Northcote, Bt | 4 August 1886 | office abolished 1888 |
| Secretary of State for the Colonies | Edward Stanhope | 3 August 1886 | |
| Sir Henry Holland, Bt | 14 January 1887 | created Baron Knutsford 23 February 1888 |
| Under-Secretary of State for the Colonies | The Earl of Dunraven | 3 August 1886 | |
| The Earl of Onslow | 16 February 1887 |
| Baron Henry de Worms | 20 February 1888 |
| Secretary of State for India | The Viscount Cross | 3 August 1886 | |
| Under-Secretary of State for India | Sir John Eldon Gorst | 4 August 1886 | |
| George Curzon | 9 November 1891 |
| First Lord of the Admiralty | Lord George Hamilton | 9 August 1886 | |
| Parliamentary and Financial Secretary to the Admiralty | Arthur Forwood | 9 August 1886 | |
| Civil Lord of the Admiralty | Ellis Ashmead-Bartlett | 9 August 1886 | |
| President of the Board of Agriculture | Henry Chaplin | 9 September 1889 | |
| Chief Secretary for Ireland | Sir Michael Hicks Beach, Bt | 5 August 1886 | |
| Arthur Balfour | 7 March 1887 |
| William Jackson | 9 November 1891 |
| Lord Lieutenant of Ireland | The Marquess of Londonderry | 3 August 1886 | |
| The Earl of Zetland | 30 July 1889 |
| Lord Chancellor of Ireland | The Lord Ashbourne | 3 August 1886 | |
| Chancellor of the Duchy of Lancaster | The Viscount Cranbrook | 3 August 1886 | |
| Lord John Manners | 16 August 1886 | succeeded as 7th Duke of Rutland 4 March 1888 |
| President of the Local Government Board | Charles Ritchie | 3 August 1886 | entered the Cabinet April 1887 |
| Parliamentary Secretary to the Local Government Board | Walter Long | 3 August 1886 | |
| Minister without Portfolio | Sir Michael Hicks Beach, Bt | 7 March 1887 – 20 February 1888 | |
| Secretary for Scotland | Arthur Balfour | 5 August 1886 | entered the Cabinet November 1886 |
| The Marquess of Lothian | 11 March 1887 | |
| President of the Board of Trade | Sir Frederick Stanley | 3 August 1886 | created Lord Stanley of Preston 27 August 1886 |
| Sir Michael Hicks Beach, Bt | 21 February 1888 | |
| Parliamentary Secretary to the Board of Trade | Baron Henry de Worms | 4 August 1886 | |
| The Earl of Onslow | 21 February 1888 |
| The Lord Balfour of Burleigh | 1 January 1889 |
| Vice-President of the Committee on Education | Sir Henry Holland, Bt | 3 August 1886 | |
| Sir William Hart Dyke, Bt | 25 January 1887 |
| Paymaster-General | The Earl Beauchamp | 19 August 1886 | |
| The Earl Brownlow | March 1887 |
| The Earl of Jersey | 1889 |
| The Lord Windsor | December 1890 |
| Postmaster-General | Henry Cecil Raikes | 19 August 1886 | |
| Sir James Fergusson, Bt | 21 September 1891 |
| First Commissioner of Works | David Robert Plunket | 5 August 1886 | |
| Attorney General | Sir Richard Webster | 5 August 1886 | |
| Solicitor General | Sir Edward Clarke | 6 August 1886 | |
| Judge Advocate General | William Thackeray Marriott | 9 August 1886 | |
| Lord Advocate | John Macdonald | 6 August 1886 | |
| James Robertson | 27 October 1888 |
| vacant | 20 August 1891 |
| Sir Charles Pearson | 1 October 1891 |
| Solicitor General for Scotland | James Robertson | 6 August 1886 | |
| Moir Tod Stormonth Darling | 27 October 1888 |
| Sir Charles Pearson | 31 October 1890 |
| Andrew Murray | 1 October 1891 |
| Attorney General for Ireland | Hugh Holmes | August 1886 | |
| John George Gibson | 1887 |
| Peter O'Brien | 1888 |
| Dodgson Hamilton Madden | 1890 |
| Solicitor General for Ireland | John George Gibson | August 1886 | |
| Dodgson Hamilton Madden | 1888 |
| John Atkinson | 1890 |
| Edward Carson | June 1892 |
| Lord Steward of the Household | The Earl of Mount Edgcumbe | 16 August 1886 | |
| Lord Chamberlain of the Household | The Earl of Lathom | 5 August 1886 | |
| Vice-Chamberlain of the Household | Viscount Lewisham | 5 August 1886 | |
| Lord Burghley | 24 November 1891 |
| Master of the Horse | The Duke of Portland | 9 August 1886 | |
| Treasurer of the Household | Viscount Folkestone | 5 August 1886 | succeeded as 5th Earl of Radnor 11 March 1889 |
| Lord Walter Gordon-Lennox | 20 November 1891 | |
| Comptroller of the Household | Lord Arthur Hill | 5 August 1886 | |
| Captain of the Gentlemen-at-Arms | The Viscount Barrington | 5 August 1886 | |
| The Earl of Rosslyn | 24 November 1886 |
| The Earl of Yarborough | 11 August 1890 |
| Captain of the Yeomen of the Guard | The Earl of Kintore | 5 August 1886 | |
| The Earl of Limerick | 29 January 1889 |
| Master of the Buckhounds | The Earl of Coventry | 16 August 1886 | |
| Mistress of the Robes | The Duchess of Buccleuch | 5 August 1886 | |
| Lords in Waiting | The Earl of Onslow | 5 August 1886 – 21 February 1887 | |
| The Earl of Limerick | 5 August 1886 – 29 January 1889 |
| The Lord Henniker | 5 August 1886 – 11 August 1892 |
| The Earl of Hopetoun | 5 August 1886 – 12 August 1889 |
| The Lord Elphinstone | 5 August 1886 – 11 August 1892 |
| The Lord de Ros | 5 August 1886 – 11 August 1892 |
| The Earl Waldegrave | 5 August 1886 – 11 August 1892 |
| The Lord Balfour of Burleigh | 21 February 1887 – 18 March 1889 |
| The Earl of Romney | 5 February 1889 – 11 August 1892 |
| The Viscount Torrington | 18 March 1889 – 20 October 1889 |
| The Lord Churchill | 12 August 1889 – 11 August 1892 |
| The Lord de Ramsey | 10 March 1890 – 11 August 1892 |
| Extra Lord in Waiting | The Lord Sackville | 1 October 1876 – 1 October 1888 | |