Missouri Route 22

Route 22
Route information
Maintained by MoDOT
Length:	23 mi (37 km)
Existed:	1922 – present
Major junctions
East end:	Route 15 in Mexico
West end:	US 63/Route F south of Clark
Highway system
Missouri State Highway System Interstate US State Supplemental ← Route 21 Route 23 →

Route 22 is a highway in central Missouri. Its eastern terminus is at Route 15 in Mexico; its western terminus is at U.S. Route 63 south of Clark on the Randolph/Boone county line. Route 22 was one of the original 1922 state highways and originally had an eastern terminus at Route 9 (now U.S. Route 61) in Louisiana. This section was replaced by U.S. Route 54 in 1926.

Major intersections

County	Location	mi	km	Destinations	Notes
Boone	​			US 63 / Route F west – Moberly, Columbia	interchange
Audrain	​			Route 151 north – Madison	west end of Route 151 overlap
	​			Route 151 south	east end of Route 151 overlap
Boone	Centralia			Route 124 west / Route 151 north – Hallsville
Audrain	Mexico			Route 15 north (Western Street) – Paris	west end of Route 15 overlap
				US 54 Bus. east (Boulevard Street)	west end of US 54 Bus. overlap
				US 54 – Bowling Green, Jefferson City	interchange; east end of US 54 Bus. / Route 15 overlap
1.000 mi = 1.609 km; 1.000 km = 0.621 mi