Pentethylcyclanone

Pentethylcyclanone
Identifiers

IUPAC name 2-(Cyclopenten-1-yl)-2-(2-morpholin-4-ylethyl)cyclopentan-1-one
Synonyms	Ciclexanona, Cyclexanonum, Cyclexanone
CAS Number	15301-52-7^Y
PubChem (CID)	10355398
ChemSpider	8530850^Y
Chemical and physical data
Formula	C₁₆H₂₅NO₂
Molar mass	263.3752 g/mol
3D model (Jmol)	Interactive image
SMILES C1CC=C(C1)C2(CCCC2=O)CCN3CCOCC3
InChI InChI=1S/C16H25NO2/c18-15-6-3-7-16(15,14-4-1-2-5-14)8-9-17-10-12-19-13-11-17/h4H,1-3,5-13H2^Y Key:KUOYUNPLUMKQIF-UHFFFAOYSA-N^Y

Pentethylcyclanone is an antitussive medication.

Synthesis

Pentethylcyclanone can be prepared by alkylation of the anion of the self-condensation product of cyclopentanone with N-(2-chloroethyl)-morpholine.^[1]

Cyclexanone synthesis

References

↑ DE 1059901 (1959), Ciba Geigy

Cough and cold preparations (R05)

Expectorants

Mucolytics

Cough suppressants

Opium alkaloids, opioids, and derivatives	Acetyldihydrocodeine Benzylmorphine Butorphanol Codeine Dextromethorphan Dihydrocodeine Dimemorfan Droxypropine Ethylmorphine Heroin Hydrocodone Hydromorphone Isoaminile Laudanum Levomethadone Levopropoxyphene Methadone Nicocodeine Nicodicodeine Normethadone Noscapine Pholcodine Thebacon Tipepidine

Other	Benzonatate Benproperine Bibenzonium bromide Butamirate Clobutinol Clofedanol Cloperastine Diphenhydramine Dibunate Dimethoxanate Dropropizine Fedrilate Glaucine Levodropropizine Meprotixol Morclofone Nepinalone Oxolamine Oxeladin Pentoxyverine Pipazetate Prenoxdiazine Piperidione Zipeprol

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